LORAZEPAM PRESERVATIVE FREE

Post-LOE

lorazepam

Quantum Genomics

ANDAINJECTIONINJECTABLE

Approved

Jul 2005

Lifecycle

Post-LOE

Competitive Pressure

30/100

Clinical Trials

Data completeness

4/8 — Partial

LORAZEPAM PRESERVATIVE FREE (lorazepam) by Quantum Genomics is clinical pharmacology studies in healthy volunteers show that in single high doses lorazepam has a tranquilizing action on the central nervous system with no appreciable effect on the respiratory or cardiovascular systems. Approved for benzodiazepine [epc]. First approved in 2005.

Drug data last refreshed 22h ago

Mechanism of Action

CLINICAL PHARMACOLOGY Studies in healthy volunteers show that in single high doses lorazepam has a tranquilizing action on the central nervous system with no appreciable effect on the respiratory or cardiovascular systems. Lorazepam is readily absorbed with an absolute bioavailability of 90%. Peak…

Indications

Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.

Clinical Trials (10)

NCT02239380Phase 3Completed

Lorazepam for the Treatment of Status Epilepticus or Repetitive Status Epilepticus in Japan

Started Nov 2014

26 enrolled

Status Epilepticus

NCT01994668Phase 1Completed

Phase 1 Study to Characterize the Safety and Pharmacokinetics of Single Intravenous Dose of Lorazepam in Healthy Japanese Adult Subjects

Started Jan 2014

8 enrolled

Healthy

NCT02147548Phase 3Completed

Evaluation of the Effects of Etifoxine 100 mg and Lorazepam 2 mg on Vigilance and Cognitive Functions in the Elderly

Started Dec 2013

31 enrolled

Healthy Volunteers

NCT01275144Phase 1Completed

A Study of the Effect of LY2216684 on Lorazepam

Started Dec 2010

28 enrolled

Major Depressive Disorder

NCT00621478Phase 2/3Completed

Efficacy and Safety Study Comparing Lorazepam and Diazepam for Children in the Emergency Department With Seizures (Status 2)

Started Feb 2008

259 enrolled

Status Epilepticus

Worked on LORAZEPAM PRESERVATIVE FREE at Quantum Genomics? Share your interview experience or compensation data (+7 days Pro)

Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.