LOPRESSOR (metoprolol tartrate) by Rubicon Biotechnology is 12. First approved in 2025.
Drug data last refreshed 5h ago · AI intelligence enriched 6d ago
Lopressor (metoprolol tartrate) is a beta-1 selective adrenergic receptor blocking agent indicated for hypertension, angina pectoris, and heart failure. It works by competitively antagonizing catecholamines at cardiac adrenergic sites, reducing heart rate, cardiac output, and myocardial oxygen demand. The oral solution formulation enables flexible dosing for patients with swallowing difficulties or titration needs.
Early-stage product launch with modest Part D uptake signals limited immediate commercial scale; team build and field expansion will depend on label penetration and formulation differentiation vs. existing metoprolol products.
12.1 Mechanism of Action Metoprolol is a beta 1 -selective (cardioselective) adrenergic receptor blocking agent. This preferential effect is not absolute, however, and at higher plasma concentrations, metoprolol also inhibits beta 2 -adrenoreceptors, chiefly located in the bronchial and vascular…
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Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
A Crossover Study to Evaluate the Effect of JNJ-54452840 on Pharmacodynamics of Metoprolol Tartrate Immediate-Release in Healthy Participants
Food Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg to Lopressor HCT® Tablets 100/50 mg
Fasting Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg and Lopressor HCT® Tablets 100/50 mg
Fed Study of Metoprolol Tartrate Tablets 25 mg and Lopressor® 50 mg
Fed Study of Metoprolol Tartrate Tablets 100 mg and Lopressor® 100 mg
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Upgrade to Pro — $25/moWorking on Lopressor at launch offers exposure to formulation differentiation strategy and niche market penetration in a mature category; limited clinical development and modest reimbursement ($370K Part D spend) signal a smaller team with constrained resources compared to growth-stage brands. Career growth depends on ability to expand label adoption and develop adjacent formulations rather than portfolio innovation.