NDAORALSOLUTION
Approved
Apr 2025
Lifecycle
Launch
Competitive Pressure
30/100
Clinical Trials
1
Mechanism of Action
12.1 Mechanism of Action Metoprolol is a beta 1 -selective (cardioselective) adrenergic receptor blocking agent. This preferential effect is not absolute, however, and at higher plasma concentrations, metoprolol also inhibits beta 2 -adrenoreceptors, chiefly located in the bronchial and vascular…
Indications (9)
hypertension in adult patientsto lower blood pressurethe long-term treatment of angina pectoris in adult patientsto reduce angina attacksto improve exercise tolerancethe treatment of hemodynamically stable adult patients with definitesuspected acute myocardial infarction to reduce cardiovascular mortalityconjunction with intravenous metoprololhypertension
Clinical Trials (1)
A Crossover Study to Evaluate the Effect of JNJ-54452840 on Pharmacodynamics of Metoprolol Tartrate Immediate-Release in Healthy Participants
Started Jul 2013
0Healthy