LOPRESSOR

Launch

metoprolol tartrate

NDAORALTABLET
Approved
Aug 2025
Lifecycle
Launch
Competitive Pressure
30/100
Clinical Trials
1

Mechanism of Action

12.1 Mechanism of Action Metoprolol is a beta 1 -selective (cardioselective) adrenergic receptor blocking agent. This preferential effect is not absolute, however, and at higher plasma concentrations, metoprolol also inhibits beta 2 -adrenoreceptors, chiefly located in the bronchial and vascular…

Indications (3)

the treatment of hemodynamically stable adult patients with myocardial infarctionto reduce the risk of cardiovascular mortalitythe treatment of hemodynamically stable adult patients with myocardial infarction (MI) to reduce cardiovascular mortality

Clinical Trials (1)

NCT01902550Phase 1Withdrawn

A Crossover Study to Evaluate the Effect of JNJ-54452840 on Pharmacodynamics of Metoprolol Tartrate Immediate-Release in Healthy Participants

Started Jul 2013
0
Healthy
External Resources
DailyMed
Full prescribing information
FDA Drugs@FDA
FDA approval history
RxNorm
Drug nomenclature & identifiers