NDAORALTABLET
Approved
Dec 1984
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Data completeness
2/8 — Basic
Drug data last refreshed 19h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LOPRESSOR HCT is a fixed-dose combination of metoprolol tartrate (beta-blocker) and hydrochlorothiazide (thiazide diuretic) administered orally as a tablet. It is indicated for hypertension management, leveraging dual mechanisms to reduce blood pressure through beta-blockade and diuretic action. This combination targets patients requiring multi-drug therapy for blood pressure control.
LOE Approaching
As LOE approaches, the commercial team is likely in defensive/maintenance mode with reduced hiring; focus shifts to generic transition planning and cost management.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (2)
Fasting Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg and Lopressor HCT® Tablets 100/50 mg
Started Jan 2003
32 enrolled
Healthy
Food Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets 100/50 mg to Lopressor HCT® Tablets 100/50 mg
Started Jan 2003
32 enrolled
Healthy
Career Relevance
Working on LOPRESSOR HCT as LOE approaches offers limited growth opportunities but valuable experience in mature product management, generic transition planning, and cost-containment strategy. Career advancement likely requires lateral moves to growth-stage products within the Bausch Health portfolio or external transition to other organizations.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.