NDAORALTABLET
Approved
Dec 1984
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
1/8 — Limited
Drug data last refreshed 1w ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LOPRESSOR HCT is a fixed-dose combination tablet containing metoprolol tartrate (a beta-blocker) and hydrochlorothiazide (a thiazide diuretic) approved in 1984 for oral treatment of hypertension. The combination leverages complementary mechanisms: metoprolol reduces heart rate and cardiac output while hydrochlorothiazide promotes sodium and water excretion to lower blood pressure. This dual-action formulation is designed for patients requiring sustained antihypertensive control.
LOE Approaching
As loss of exclusivity approaches, the brand team is likely consolidating; expect reduced headcount and shift from growth-focused to defensive positioning strategies.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on LOPRESSOR HCT offers limited career advancement opportunity due to its LOE-approaching status and commodity-like market position. Professionals assigned to this product should expect responsibility for defensive market management, generic transition planning, and cost optimization rather than growth-oriented innovation roles.
Brand ManagerField Sales Representative
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.