LODOCO

Growth

colchicine tablets 0.5 mg

NDAORALTABLETPriority Review

Approved

Jun 2023

Lifecycle

Growth

Competitive Pressure

0/100

Mechanism of Action

12. CLINICAL PHARMACOLOGY 12.1 Mechanism of Action The mechanism of action of colchicine in the prevention of major cardiovascular events is not understood. However, it is known that colchicine disrupts cytoskeletal functions through inhibition of β-tubulin polymerization into microtubules and…

Pharmacologic Class:

Alkaloid

Indications (5)

myocardial infarction (MI)stroke coronary revascularization cardiovascular death in adult patients with established atherosclerotic disease multiple risk factors for cardiovascular disease

Loss of Exclusivity

LOE Date

May 9, 2034

99 months away

Patent Expiry

May 9, 2034

Patent Records (5)

Patent #	Expiry	Type	Use Code
9744144	Nov 1, 2033		U-3643
10206891	Nov 1, 2033		U-3641
10265281	Nov 1, 2033		U-3639
10842762	Nov 1, 2033		U-3640
11026899	Nov 1, 2033		U-3639

Company

Slovakia - Senec

External Resources

Full prescribing information

FDA approval history

Drug nomenclature & identifiers