NDATOPICALPATCH
Approved
Mar 1999
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
5/8 — Partial
LIDODERM (lidocaine) by Teikoku Seiyaku is clinical pharmacology pharmacodynamics lidocaine is an amide-type local anesthetic agent and is suggested to stabilize neuronal membranes by inhibiting the ionic fluxes required for the initiation and conduction of impulses. First approved in 1999.
Drug data last refreshed 2h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LIDODERM is a topical lidocaine patch (5%) approved in 1999 for localized pain relief via transdermal delivery. It works by stabilizing neuronal membranes and inhibiting ionic fluxes required for pain signal conduction, producing analgesia without complete sensory block. The patch delivers minimal systemic absorption (~3% of applied dose), making it a low-risk topical option for post-herpetic neuralgia and localized pain conditions.
$0.003BPart D
LOE ApproachingProduct is in late-stage lifecycle with modest Part D spending ($3M, 2215 claims in 2023), indicating shrinking team and focus on defending market share against generics.
Mechanism of Action
CLINICAL PHARMACOLOGY Pharmacodynamics Lidocaine is an amide-type local anesthetic agent and is suggested to stabilize neuronal membranes by inhibiting the ionic fluxes required for the initiation and conduction of impulses. The penetration of lidocaine into intact skin after application of…
Worked on LIDODERM at Teikoku Seiyaku? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.