NDATOPICALPATCH
Approved
Mar 1999
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
5/8 — Partial
LIDODERM (lidocaine) by Teikoku Seiyaku is clinical pharmacology pharmacodynamics lidocaine is an amide-type local anesthetic agent and is suggested to stabilize neuronal membranes by inhibiting the ionic fluxes required for the initiation and conduction of impulses. First approved in 1999.
Drug data last refreshed 8h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LIDODERM is a topical lidocaine 5% patch approved in 1999 for localized pain relief, containing an amide-type local anesthetic that stabilizes neuronal membranes to inhibit pain impulse conduction. The patch delivers minimal systemic absorption (3% of applied dose), producing local analgesia without complete sensory block, making it suitable for postherpetic neuralgia and other localized pain conditions. Lidocaine penetrates intact skin to concentrations that produce therapeutic topical effect while maintaining a safety profile with negligible systemic exposure.
$0.003BPart D
LOE ApproachingProduct approaching loss of exclusivity with modest Medicare spend ($3M) and low claim volume, signaling a mature market with declining team investment.
Mechanism of Action
CLINICAL PHARMACOLOGY Pharmacodynamics Lidocaine is an amide-type local anesthetic agent and is suggested to stabilize neuronal membranes by inhibiting the ionic fluxes required for the initiation and conduction of impulses. The penetration of lidocaine into intact skin after application of…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.