LIDOCAINE

Post-LOE

lidocaine

ANDATOPICALOINTMENT
Approved
May 2011
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
13

Mechanism of Action

Mechanism of action Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.

Pharmacologic Class:

Amide Local Anesthetic

Clinical Trials (5)

NCT07032597Phase 3Active Not Recruiting

A Study to Assess Safety and Effectiveness of HArmonyCa Lidocaine Injectable Gel for Restoration and/or Creation of Mid-Face Volume in Adult Participants

Started May 2025
252 enrolled
Mid Face Volume Deficit
NCT04614610Phase 2Unknown

Lidocaine Intravenous in the Emergency Department For Sickle Cell Crisis

Started Jan 2024
100 enrolled
Sickle Cell DiseaseSickle Cell CrisisPain, Acute
NCT04033562Phase 4Terminated

The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis

Started Jan 2020
NCT04224649N/AUnknown

To Evaluate the Efficacy and Safety of Injection With HARA as Compared to Restylane® Lidocaine in Temporary Correction of Nasolabial Folds

Started Apr 2019
67 enrolled
Nasolabial FOLD
NCT03757078N/ACompleted

Study to Find Out How Symptoms Severity Changes During the Standard Course of Treatment With the Cream Relief Pro and Suppositories Relief Pro (Active Ingredients Are Fluocortolone + Lidocaine) in Patients Suffering From Twisted and Bulging Veins in the Rectal Area (Acute Hemorrhoids)

Started Nov 2018
1,000 enrolled
Acute Hemorrhoids