LIDEX
LOE ApproachingNDATOPICALOINTMENT
Approved
Sep 1971
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
LIDEX by Alvogen is clinical pharmacology: mechanism of action: lidexagel® 5% gel releases lidocaine from a mild acidic vehicle to stabilize the neuronal membrane by inhibiting the ionic fluxes required for initiation and conduction of impulses, thereby effecting local anesthetic action. First approved in 1971.
Drug data last refreshed 21h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LIDEX is a topical lidocaine 5% ointment that delivers local anesthetic action through a mild acidic vehicle formulation. It works by stabilizing neuronal membranes to inhibit ionic fluxes required for impulse initiation and conduction. The acidic pH provides protection against alkaline irritants and supports healing in topical applications.
LOE Approaching
Product lifecycle approaching loss of exclusivity with limited commercial momentum; team likely focused on cost management and transition planning rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY: Mechanism of Action: LidexaGel® 5% Gel releases lidocaine from a mild acidic vehicle to stabilize the neuronal membrane by inhibiting the ionic fluxes required for initiation and conduction of impulses, thereby effecting local anesthetic action. A mild acidic vehicle lowers…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.