NDAINJECTIONINJECTABLEPriority Review
Approved
Jul 1950
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
Priority Review
LEVOPHED (norepinephrine bitartrate) by Pfizer is (alpha-adrenergic action) and an inotropic stimulator of the heart and dilator of coronary arteries (beta-adrenergic action). First approved in 1950.
Drug data last refreshed 3h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LEVOPHED (norepinephrine bitartrate) is a classic catecholamine vasopressor approved in 1950 for acute hypotension and shock states. It works through dual alpha-adrenergic (vasoconstriction) and beta-adrenergic (inotropic and coronary vasodilation) mechanisms. This is an essential ICU and acute care injectable with deep historical entrenchment in critical care protocols.
LOE Approaching
As LOE approaches, brand teams are managing transition to generic competition; team consolidation and focus on differentiation through IV access solutions or formulation variants likely underway.
Mechanism of Action
(alpha-adrenergic action) and an inotropic stimulator of the heart and dilator of coronary arteries (beta-adrenergic action).
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on LEVOPHED offers stability in a mission-critical, standard-of-care franchise with deep healthcare system relationships and protocol entrenchment, but limited growth trajectory. Career value lies in mastering hospital dynamics, payer negotiations, and defensive market strategy rather than launching innovation or expanding patient populations.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.