NDAINJECTIONINJECTABLEPriority Review
Approved
Jul 1950
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
Priority Review
LEVOPHED (norepinephrine bitartrate) by Pfizer is (alpha-adrenergic action) and an inotropic stimulator of the heart and dilator of coronary arteries (beta-adrenergic action). First approved in 1950.
Drug data last refreshed 19h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LEVOPHED (norepinephrine bitartrate) is a classic sympathomimetic amine administered intravenously to manage acute hypotension and shock states. It works through dual alpha-adrenergic (vasoconstriction) and beta-adrenergic (inotropic and coronary vasodilation) mechanisms to restore blood pressure and tissue perfusion. This foundational critical care agent has been a standard of care since 1950.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30%); brand team likely focused on transition planning and cost optimization rather than expansion.
Mechanism of Action
(alpha-adrenergic action) and an inotropic stimulator of the heart and dilator of coronary arteries (beta-adrenergic action).
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on LEVOPHED offers limited growth trajectory but stable, specialized roles in hospital sales, managed care, and operations. Career professionals should expect focus on defensive market positioning, cost management, and relationship-based selling rather than innovation or territory expansion.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.