LEFLUNOMIDE (leflunomide) by Teva is 12. Approved for antirheumatic agent [epc]. First approved in 2005.
Drug data last refreshed 19h ago
12.1 Mechanism of Action Leflunomide is an isoxazole immunomodulatory agent that inhibits dihydroorotate dehydrogenase (a mitochondrial enzyme involved in de novo pyrimidine synthesis) and has antiproliferative activity. Several in vivo and i n vitro experimental models have demonstrated an…
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A Study of the Effectiveness of Additional Risk Minimization Measures Related to ARAVA® (Leflunomide) in Saudi Arabia
Bioequivalence Study of Generic Leflunomide 20 mg Film-coated Tablets and Reference Product Under Fasting Conditions
Leflunomide Treatment for IgG4-RD
A Study to Compare the Efficacy and Safety of Tacrolimus Capsules With Leflunomide Tablets in Lupus Nephritis Patients
Leflunomide EfficAcy Response Related to Dosing Regimen in Early Rheumatoid Arthritis