LAZCLUZE

Growth

lazertinib

NDAORALTABLETPriority Review
Approved
Aug 2024
Lifecycle
Growth
Competitive Pressure
0/100
Clinical Trials
16

Mechanism of Action

Kinase Inhibitors

Pharmacologic Class:

Kinase Inhibitor

Clinical Trials (5)

NCT06667076Phase 2Recruiting

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Started Dec 2024
480 enrolled
Carcinoma, Non-Small-Cell Lung
NCT06120140Phase 2Recruiting

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib

Started Feb 2024
300 enrolled
Carcinoma, Non-Small-Cell Lung
NCT05896683Phase 1Completed

A Study of Lazertinib (JNJ-73841937) Tablet in Healthy Adult Participants

Started May 2023
72 enrolled
Healthy
NCT05299125Phase 2Active Not Recruiting

Amivantamab, Lazertinib, and Pemetrexed for First-line Treatment of Recurrent/Metastatic Non-small Cell Lung Cancers With Epidermal Growth Factor Receptor Mutations

Started May 2023
54 enrolled
Metastatic Non-small Cell Lung Cancers
NCT05601973Phase 2Active Not Recruiting

Amivantamab, Lazertinib and Bevacizumab in Patients With EGFR-mutant Advanced Non-small Cell Lung Cancer With Progression on Previous Third-generation EGFR-TKI

Started Mar 2023
60 enrolled
Non Small Cell Lung Cancer

Loss of Exclusivity

LOE Date
Aug 1, 2041
187 months away
Patent Expiry
Aug 1, 2041
Exclusivity Expiry
Aug 19, 2029

Patent Records (5)

Patent #ExpiryTypeUse Code
9593098
Oct 13, 2035
SubstanceProduct
U-3985
11981659
Apr 18, 2038
U-3985
11453656
Apr 18, 2038
SubstanceProduct
12318390
Apr 18, 2038
Product
11879013
May 21, 2040
U-3985