LASIX
LOE ApproachingNDAINJECTIONINJECTABLEPriority Review
Approved
Mar 1968
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
5/8 — Partial
Priority Review
LASIX by Sanofi is 12. Approved for edema in adult patients with chronic heart failure. First approved in 1968.
Drug data last refreshed 3d ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LASIX (furosemide) is a loop diuretic that inhibits sodium and chloride reabsorption in the proximal and distal tubules and loop of Henle, producing potent diuresis. It is indicated for heart failure, volume overload, respiratory failure, and hypernatremia. The drug works by blocking tubular reabsorption of electrolytes, driving rapid fluid excretion.
$0.61MPart D
LOE ApproachingDeclining
Life-cycle approaching end-of-exclusivity with minimal branded job growth; team focus likely on generic transition and cost management.
Mechanism of Action
12.1 Mechanism of Action Furosemide primarily inhibits the reabsorption of sodium and chloride in the proximal and distal tubules and in the loop of Henle. The high degree of diuresis is largely due to the unique site of action. The action on the distal tubule is independent of any inhibitory…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.