NDAORALTABLETPriority Review
Approved
Jul 1966
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
5/8 — Partial
Priority Review
LASIX (furosemide) by Bausch Health is clinical pharmacology investigations into the mode of action of lasix have utilized micropuncture studies in rats, stop flow experiments in dogs and various clearance studies in both humans and experimental animals. First approved in 1966.
Drug data last refreshed 17h ago · AI intelligence enriched 20h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LASIX (furosemide) is a loop diuretic approved in 1966 that inhibits sodium and chloride reabsorption in the loop of Henle and distal tubule, producing rapid onset diuresis within 1 hour. It is used primarily for edema associated with congestive heart failure, liver cirrhosis, and renal disease, as well as hypertension management. The drug's high efficacy derives from its unique site of action independent of carbonic anhydrase or aldosterone inhibition.
$0.61MPart D
LOE ApproachingLong-established generic product with minimal Part D volume and declining proprietary margins; brand team likely focused on cost management and market stabilization rather than expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY Investigations into the mode of action of LASIX have utilized micropuncture studies in rats, stop flow experiments in dogs and various clearance studies in both humans and experimental animals. It has been demonstrated that LASIX inhibits primarily the absorption of sodium and…
Worked on LASIX at Bausch Health? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.