NDAORALTABLETPriority Review
Approved
Jul 1966
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
5/8 — Partial
Priority Review
LASIX (furosemide) by Bausch Health is clinical pharmacology investigations into the mode of action of lasix have utilized micropuncture studies in rats, stop flow experiments in dogs and various clearance studies in both humans and experimental animals. First approved in 1966.
Drug data last refreshed 43m ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LASIX (furosemide) is a loop diuretic that inhibits sodium and chloride absorption in the proximal tubule, distal tubule, and loop of Henle, producing rapid diuresis within 1 hour. It is indicated for edema associated with congestive heart failure, liver cirrhosis, renal disease, and hypertension management. The drug achieves peak effect within 1-2 hours with a 6-8 hour duration of action.
$0.61MPart D
LOE ApproachingDeclining
As a 58-year-old generic-competitive product approaching loss of exclusivity, LASIX faces significant volume pressure and declining team investment despite sustained utilization.
Mechanism of Action
CLINICAL PHARMACOLOGY Investigations into the mode of action of LASIX have utilized micropuncture studies in rats, stop flow experiments in dogs and various clearance studies in both humans and experimental animals. It has been demonstrated that LASIX inhibits primarily the absorption of sodium and…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.