NDAORALTABLET, EXTENDED RELEASE
Approved
Jan 2010
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Clinical Trials (5)
A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
Started Oct 2025
424 enrolled
ManiaBipolar Disorder
A Study to Evaluate the Effects of Lithium, Valproic Acid, and Lamotrigine on the Pharmacokinetics of KarXT and Effects of KarXT on the Pharmacokinetics of Lithium, Valproic Acid, and Lamotrigine in Healthy Participants
Started Dec 2024
A Study in Healthy Men to Test Whether BI 409306, BI 425809 or Lamotrigine Can Reverse the Memory Problems Caused by Ketamine
Started Dec 2020
40 enrolled
Healthy
Ketamine-Induced Brain Changes and Their Modulation by Lamotrigine
Started Mar 2020
75 enrolled
Emotions
Pharmacokinetics, Safety and Tolerability of Repeat Dosing Lamotrigine in Healthy Chinese Subjects
Started Sep 2015
16 enrolled
Bipolar Disorder