LACTULOSE

Post-LOE

lactulose

ANDAORALFOR SOLUTION
Approved
Dec 1997
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
6

Mechanism of Action

Osmotic Activity

Pharmacologic Class:

Osmotic Laxative

Clinical Trials (5)

NCT03666546Phase 4Completed

Blood Glucose Response After Oral Intake of Lactulose in Mildly Constipated Patients With Diabetes Mellitus Type 2

Started Nov 2018
24 enrolled
Diabetes Mellitus, Type 2
NCT03515044Phase 2Completed

Rifaximin Soluble Solid Dispersion (SSD) Tablets Plus Lactulose for the Treatment of Overt Hepatic Encephalopathy (OHE)

Started Sep 2018
NCT02968498N/ACompleted

Blood Glucose Response After Oral Intake of Lactulose in Healthy Volunteers

Started Nov 2016
24 enrolled
Blood Glucose
NCT02377947N/ACompleted

A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study]

Started Dec 2015
50 enrolled
Hepatic Encephalopathy
NCT02228616Phase 4Completed

Efficacy and Safety of Prucalopride in Combination With Polyethylene Glycol or Lactulose in Women With Chronic Constipation

Started Oct 2014
280 enrolled
Constipation