NDAOPHTHALMICINSERT
Approved
Jun 1981
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
5/8 — Partial
LACRISERT (hydroxypropyl cellulose) by Bausch + Lomb is clinical pharmacology pharmacodynamics lacrisert acts to stabilize and thicken the precorneal tear film and prolong the tear film breakup time which is usually accelerated in patients with dry eye states. Approved for moderate to severe dry eye syndromes, including keratoconjunctivitis sicca. First approved in 1981.
Drug data last refreshed 3d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LACRISERT is a hydroxypropyl cellulose ophthalmic insert approved in 1981 for moderate to severe dry eye syndromes, including keratoconjunctivitis sicca. It works by stabilizing and thickening the precorneal tear film, prolonging tear film breakup time, and lubricating/protecting the eye. The insert dissolves gradually over 14-24 hours, providing sustained relief superior to artificial tears.
$0.017BPart D
LOE ApproachingThis product is approaching loss of exclusivity with minimal current spending and very low claim volume, indicating a small, mature franchise with limited team growth opportunity.
Mechanism of Action
CLINICAL PHARMACOLOGY Pharmacodynamics LACRISERT acts to stabilize and thicken the precorneal tear film and prolong the tear film breakup time which is usually accelerated in patients with dry eye states. LACRISERT also acts to lubricate and protect the eye. LACRISERT usually reduces the signs and…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.