NDATOPICALLOTION
Approved
Apr 1985
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
LAC-HYDRIN (ammonium lactate) by PharmaIN is clinical pharmacology lactic acid is an alpha-hydroxy acid. Approved for ichthyosis vulgaris, xerosis. First approved in 1985.
Drug data last refreshed 3d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
LAC-HYDRIN (ammonium lactate) is a topical lotion containing an alpha-hydroxy acid that acts as a humectant to hydrate the stratum corneum and decrease corneocyte cohesion. It is indicated for ichthyosis vulgaris and xerosis, common dry skin conditions. The drug works through normal skin physiology, with minimal systemic absorption (6.1% after 68 hours in vitro).
LOE Approaching
Product is approaching loss of exclusivity, signaling potential team restructuring and transition to generic defense or portfolio repositioning strategies.
Mechanism of Action
CLINICAL PHARMACOLOGY Lactic acid is an alpha-hydroxy acid. It is a normal constituent of tissues and blood. The alpha-hydroxy acids (and their salts) are felt to act as humectants when applied to the skin. This property may influence hydration of the stratum corneum. In addition, lactic acid, when…
Indications (2)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.