KORSUVA
Peakdifelikefalin
NDAINTRAVENOUSSOLUTIONPriority Review
Approved
Aug 2021
Lifecycle
Peak
Competitive Pressure
0/100
Data completeness
5/8 — Partial
Priority Review
KORSUVA (difelikefalin) is (kor) agonist. Approved for moderate-to-severe pruritus associated with chronic kidney disease (ckd-ap) in adults undergoing hemodialysis (hd). First approved in 2021.
Drug data last refreshed 3h ago · AI intelligence enriched 2mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
KORSUVA (difelikefalin) is a kappa opioid receptor (KOR) agonist approved for moderate-to-severe pruritus (itching) associated with chronic kidney disease in adults undergoing hemodialysis. Administered intravenously, it represents a novel mechanism for treating CKD-associated pruritus, though the precise relationship between KOR activation and therapeutic benefit remains incompletely characterized.
Peak6.1 years to LOE
Product is at peak commercial phase with no direct competitors currently, offering a stable but specialized market opportunity for a niche dialysis population.
Mechanism of Action
(KOR) agonist. The relevance of KOR activation to therapeutic effectiveness is not known.
Career Relevance
Working on KORSUVA offers the rare advantage of a monopoly market position in a specialized but stable indication; careers here focus on driving adoption in dialysis centers and managing a niche patient population. The product lifecycle is in peak commercial phase with 6+ years of patent protection, making it a predictable but non-growth opportunity for professionals seeking stability over rapid expansion.
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.