NDAORALFOR SUSPENSION
Approved
Aug 2022
Lifecycle
Peak
Competitive Pressure
0/100
Data completeness
6/8 — Strong
KONVOMEP (omeprazole and sodium bicarbonate) by R-Pharm US is compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the h+/k+ atpase enzyme system at the secretory surface of the gastric parietal cell. Approved for active benign gastric ulcer ( ), risk of upper gastrointestinal (gi) bleeding in critically ill patients ( ). First approved in 2022.
Drug data last refreshed 9h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
KONVOMEP is an oral suspension combining omeprazole and sodium bicarbonate, a proton pump inhibitor that suppresses gastric acid secretion by blocking the H+/K+ ATPase enzyme system in gastric parietal cells. It is indicated for active benign gastric ulcer and prevention of upper GI bleeding in critically ill patients. The sodium bicarbonate component provides rapid acid neutralization while omeprazole delivers sustained suppression.
$0.002BPart D
Peak13.3 years to LOEProduct is at peak commercial maturity with modest Part D utilization (~4,400 claims in 2023), suggesting stable but limited market penetration requiring targeted positioning strategies.
Mechanism of Action
compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, omeprazole has…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.