KLONOPIN
LOE Approachingclonazepam
NDAORALTABLETPriority Review
Approved
Jun 1975
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Mechanism of Action
CLINICAL PHARMACOLOGY Pharmacodynamics The precise mechanism by which clonazepam exerts its antiseizure and antipanic effects is unknown, although it is believed to be related to its ability to enhance the activity of gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter in the…
Pharmacologic Class:
Benzodiazepine
Indications (4)
Clinical Trials (2)
Evaluate Pharmacokinetics Of Two Different Pharmaceutical Oral Formulations Of Alprazolam And A Clonazepam Tablet In Mexican Healthy Population
Started Oct 2008
24 enrolled
Pharmacokinetics
Study of Intranasal Clonazepam in Adult Subjects With Epileptic Seizures
Started Dec 2007
45 enrolled
Epilepsy