NDAORALTABLET, EXTENDED RELEASE
Approved
Jul 2013
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
3/8 — Basic
KHEDEZLA (desvenlafaxine) by Hikma is unknown, but is thought to be related to the potentiation of serotonin and norepinephrine in the central nervous system, through inhibition of their reuptake. First approved in 2013.
Drug data last refreshed 5h ago · AI intelligence enriched 6d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
KHEDEZLA (desvenlafaxine) is an oral extended-release SNRI antidepressant approved in 2013 that works by inhibiting the reuptake of serotonin and norepinephrine in the central nervous system. It is indicated for major depressive disorder and demonstrates linear, predictable pharmacokinetics with once-daily dosing and minimal drug-drug interactions. The drug has a clean safety profile with no QT prolongation risk and low receptor affinity for cholinergic, histaminergic, or adrenergic targets.
Peak
Product is at peak lifecycle stage under Hikma ownership with moderate competitive pressure (30/100), indicating stable market position but diminishing growth opportunities for commercial teams.
Mechanism of Action
unknown, but is thought to be related to the potentiation of serotonin and norepinephrine in the central nervous system, through inhibition of their reuptake. Non-clinical studies have shown that desvenlafaxine is a potent and selective serotonin and norepinephrine reuptake inhibitor (SNRI). 12.2…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.