KHAPZORY

Peak

levoleucovorin

NDAINTRAVENOUSPOWDER
Approved
Oct 2018
Lifecycle
Peak
Competitive Pressure
0/100

Mechanism of Action

12.1 Mechanism of Action High-Dose Methotrexate Therapy Levoleucovorin is the pharmacologically active isomer of 5-formyl tetrahydrofolic acid. Levoleucovorin does not require reduction by dihydrofolate reductase to participate in reactions utilizing folates as a source of "one-carbon" moieties.…

Indications (1)

Loss of Exclusivity

LOE Date
Mar 25, 2039
158 months away
Patent Expiry
Mar 25, 2039

Patent Records (1)

Patent #ExpiryTypeUse Code
11541012
Mar 25, 2039
Product