NDAORAL, RECTALPOWDERPriority Review
Approved
Jun 1958
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
Priority Review
KAYEXALATE (sodium polystyrene sulfonate) by ANI Pharmaceuticals is potassium ion exchange activity [moa]. First approved in 1958.
Drug data last refreshed 3d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
KAYEXALATE is a sodium polystyrene sulfonate powder administered orally or rectally that treats hyperkalemia by exchanging sodium ions for potassium ions in the gastrointestinal tract. It is indicated for patients with elevated serum potassium levels, particularly those with chronic kidney disease or acute kidney injury. The ion-exchange mechanism reduces serum potassium concentration by promoting fecal excretion.
LOE Approaching
As LOE approaches, brand team focus shifts from growth to market defense and lifecycle extension strategies; team sizes may stabilize or consolidate.
Mechanism of Action
Potassium Ion Exchange Activity
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
KAYEXALATE career opportunities are limited due to zero linked job postings and mature market position under LOE. Positions that do exist focus on brand defense, managed care negotiations, and maintaining market share against competitors and generics rather than growth or innovation.
Brand ManagerSales Representative
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.