BLASINGLE-USEVIALPriority Review
Approved
Feb 2013
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
9
Data completeness
4/8 — Partial
Priority Review
Drug data last refreshed 5h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
KADCYLA is an antibody-drug conjugate (ADC) combining trastuzumab with the microtubule-disrupting agent emtansine, designed to deliver cytotoxic payload directly to HER2-positive cancer cells. It is approved for HER2-positive breast cancer, including metastatic disease and as adjuvant therapy. The mechanism exploits HER2 overexpression to achieve targeted cytotoxicity while minimizing systemic exposure.
$4.0MPart D
PeakPeak lifecycle stage with modest Part D claims suggests mature, stable franchise requiring efficient operations and managed market defense rather than high-growth investment.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (9)
A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)
Started May 2023
30 enrolled
Metastatic Solid TumorBrain Metastases
A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer
Started Oct 2019
466 enrolled
HER2-positive Breast Cancer
Unraveling KAdcyla Resistance In Human Epidermal Growth Factor Receptor 2(HER2) Positive Advanced Breast Cancer (KATIA)
Started Jun 2018
32 enrolled
Advanced Breast Cancer
Trial of Ado-Trastuzumab Emtansine for Patients With HER2 Amplified or Mutant Cancers
Started Feb 2016
131 enrolled
Solid Tumor CancersLung CancerBladder Cancer+1 more
An Observational Study of Kadcyla Safety in Breast Cancer
Started May 2015
563 enrolled
Breast Cancer
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.