JASCAYD by Boehringer Ingelheim is 4 (pde4) with at least nine-fold preferential inhibition of the pde4b isoenzyme over pde4a, pde4c, and pde4d based on in vitro data. Approved for idiopathic pulmonary fibrosis (ipf) in adult patients, progressive pulmonary fibrosis (ppf) in adult patients. First approved in 2025.
Drug data last refreshed Yesterday
4 (PDE4) with at least nine-fold preferential inhibition of the PDE4B isoenzyme over PDE4A, PDE4C, and PDE4D based on in vitro data. PDE4 hydrolyzes and inactivates cyclic adenosine monophosphate (cAMP). Nerandomilast exerts both antifibrotic and immunomodulatory effects as PDE4B inhibition…
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