NDAORALTABLET2 Generics Approved
Approved
Mar 2015
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
7/8 — Comprehensive
JADENU (deferasirox) by Novartis is iron chelating activity [moa]. Approved for iron chelator [epc]. First approved in 2015.
Drug data last refreshed 20h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
JADENU (deferasirox) is an oral small-molecule iron chelator approved by the FDA in March 2015 for the treatment of iron overload conditions. It works by binding excess iron in the body and facilitating its excretion, addressing a critical need in patients with chronic transfusion-dependent anemias and other iron overload disorders. JADENU represents an improved formulation of the earlier EXJADE product, offering enhanced bioavailability and more convenient dosing. The drug is currently in its peak commercial lifecycle stage.
$0.0BPart D
8.5 years to LOEMechanism of Action
Iron Chelating Activity
Pharmacologic Class:
Iron Chelator
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Early and Low Dose Deferasirox (3.5 mg/kg FCT) to Suppress NTBI and LPI as Early Intervention to Prevent Tissue Iron Overload in Lower Risk MDS
Started Oct 2019
11 enrolled
Myelodysplastic Syndromes
Evaluating Low-dose Deferasirox (DFX) in Patients With Low-risk MDS Resistant or Relapsing After ESA Agents
Started Feb 2018
39 enrolled
Myelodysplasia
Safety Study of Crushed Deferasirox Film Coated Tablets in Pediatric Patients With Transfusional Hemosiderosis
Started Jan 2018
44 enrolled
Iron Overload
Study to Evaluate the Efficacy and Safety of Deferasirox Film-coated Tablet Versus Phlebotomy in Patients With Hereditary Hemochromatosis (HH)
Started Jan 2018
45 enrolled
Hereditary Hemochromatosis
Open-label, Multicenter Study Assessing Preference for Deferasirox Film-coated Tablet Compared to Dispersible Tablet
Started Jul 2017
148 enrolled
Transfusion-dependent ThalassemiaNon-transfusion-dependent Thalassemia
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.