NDAINTRAVITREALSOLUTIONPriority Review
Approved
Aug 2023
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
5
Data completeness
5/8 — Partial
Priority Review
Drug data last refreshed 8h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
IZERVAY (avacincaptad pegol) is a small-molecule intravitreal solution approved in August 2023 for ophthalmic indications. It represents a novel therapeutic approach delivered directly to the eye to address retinal pathology. The drug targets a specific mechanism implicated in age-related macular degeneration and related conditions.
$0.216MPart D
Peak7.8 years to LOEEarly commercial uptake (76 Part D claims in 2023) suggests modest initial market penetration; peak lifecycle stage indicates growth phase with opportunity for commercial team expansion.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (5)
A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular Degeneration
Started Jul 2025
17 enrolled
Geographic AtrophyAge-Related Macular Degeneration
A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy
Started Jan 2025
500 enrolled
Geographic AtrophyMacular Degeneration
Avacincaptad Pegol Open-Label Extension for Patients With Geographic Atrophy
Started Sep 2022
278 enrolled
Geographic AtrophyAge-Related Macular Degeneration
A Study of ARC1905 (Anti-C5 Aptamer) in Subjects With Dry Age-related Macular Degeneration
Started Jul 2009
47 enrolled
Dry Age-Related Macular Degeneration
ARC1905 (Anti-C5 Aptamer) Given With Lucentis 0.5 mg In People With Neovascular Age-Related Macular Degeneration
Started Oct 2008
60 enrolled
Neovascular Age-Related Macular Degeneration
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.