NDAORALTABLET
Approved
Mar 2013
Lifecycle
Peak
Competitive Pressure
8/100
Clinical Trials
21
Data completeness
5/8 — Partial
Drug data last refreshed 18m ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
INVOKANA (canagliflozin) is an oral small-molecule SGLT2 inhibitor approved in 2013 for type 2 diabetes management. It lowers blood glucose by inhibiting sodium-glucose cotransporter 2 in the kidneys, increasing urinary glucose excretion. The drug is indicated for glycemic control in adults with type 2 diabetes, often as monotherapy or in combination with other antidiabetic agents.
$0.357BPart D
PeakStable
3.2 years to LOEINVOKANA is at peak commercial maturity with $357M in annual Part D spending and 305K claims, indicating a large, established franchise requiring defensive commercial strategy against increasing competitive pressure.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (21)
Canagliflozin With Gemcitabine in Pancreatic Carcinoma
Started Oct 2023
20 enrolled
Pancreatic Cancer
A Study to Assess Safety of Canagliflozin and Metformin Hydrochloride Combination Given as a Supplement to Diet and Exercise to Improve Blood Sugar Level in Indian Adult Participants With Diabetes
Started Nov 2020
276 enrolled
Diabetes Mellitus
A Study on Impact of Canagliflozin on Health Status, Quality of Life, and Functional Status in Heart Failure
Started Mar 2020
476 enrolled
Heart Failure
A Study to Observe Clinical Effectiveness of Canagliflozin 300 mg Containing Treatment Regimens in Indian Type 2 Diabetes Participants With BMI>25 kg/m^2, in Real World Clinical Setting
Started Sep 2018
178 enrolled
Diabetes Mellitus, Type 2
Impact of a Short-term Treatment With Canagliflozin (Canacardia-HF)
Started May 2018
0Type2 DiabetesHeart Failure
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.