INLURIYO

Launch

imlunestrant

NDAORALTABLET
Approved
Sep 2025
Lifecycle
Launch
Competitive Pressure
0/100
Clinical Trials
6

Mechanism of Action

Estrogen Receptor Antagonists

Pharmacologic Class:

Estrogen Receptor Antagonist

Clinical Trials (5)

NCT07287098Phase 2Not Yet Recruiting

A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer

Started Feb 2026
600 enrolled
Breast Neoplasm Female
NCT05514054Phase 3Active Not Recruiting

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

Started Oct 2022
8,000 enrolled
Breast Neoplasms
NCT05509816Phase 1Completed

A Study of Imlunestrant (LY3484356) in Healthy Women

Started Sep 2022
20 enrolled
Healthy
NCT05444556Phase 1Completed

A Study of Imlunestrant (LY3484356) in Female Healthy Participants

Started Jul 2022
113 enrolled
Healthy
NCT05440344Phase 1Completed

A Study of Imlunestrant (LY3484356) in Female Participants With Impaired Liver Function

Started Jul 2022
27 enrolled
Hepatic InsufficiencyHealthy

Loss of Exclusivity

LOE Date
Jul 11, 2039
162 months away
Patent Expiry
Jul 11, 2039
Exclusivity Expiry
Sep 25, 2030

Patent Records (2)

Patent #ExpiryTypeUse Code
10654866
Jul 11, 2039
SubstanceProduct
U-4278
11117902
Jul 11, 2039
SubstanceProduct
U-4278