NDAORALTABLET
Approved
Jun 1979
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
1/8 — Limited
Drug data last refreshed 2d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
INDERIDE-40/25 is a fixed-dose combination tablet of propranolol hydrochloride (a non-selective beta-blocker) and hydrochlorothiazide (a thiazide diuretic) approved in 1979 for oral treatment of hypertension. The combination works synergistically to reduce blood pressure through beta-adrenergic blockade and diuretic action. This is a foundational antihypertensive agent developed during the era of multi-drug fixed-dose combinations.
LOE Approaching
Product is in late lifecycle with moderate competitive pressure (30%), indicating a mature brand team focused on retention and generic transition planning rather than growth initiatives.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on INDERIDE-40/25 offers experience in mature product management, generic defense strategies, and lifecycle optimization within a large pharmaceutical sponsor (Pfizer). Career growth on this asset comes from managing market transitions and cost-containment pressures rather than pursuing clinical innovation.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.