INCRELEX

LOE Approaching

mecasermin

Ipsen
BLASUBCUTANEOUSINJECTABLEPriority Review
Approved
Aug 2005
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1

Mechanism of Action

Insulin-like growth factor-1 (IGF-1) is a key hormonal mediator on statural growth. Under normal circumstances, growth hormone (GH) binds to its receptor in the liver, and other tissues, and stimulates the synthesis/secretion of IGF-1. In target tissues, the Type 1 IGF-1 receptor, which is…

Indications (4)

growth failure in pediatric patients 2 years of ageolder with severe primary IGF-1 deficiencygrowth hormone (GH) gene deletionolder with: severe primary IGF-1 deficiency

Clinical Trials (1)

NCT00747604N/ATerminated

IGFD Registry: A Patient Registry for Monitoring Long-term Safety and Efficacy of Increlex

Started Jun 2006
1,378 enrolled
Primary Insulin-like Growth Factor-1 Deficiency
Company
Ipsen
Ipsen
China - Tianjin
External Resources
DailyMed
Full prescribing information
FDA Drugs@FDA
FDA approval history
RxNorm
Drug nomenclature & identifiers