IMURAN

LOE Approaching

azathioprine

NDAORALTABLETPriority Review
Approved
Mar 1968
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
11

Mechanism of Action

Nucleic Acid Synthesis Inhibitors

Pharmacologic Class:

Purine Antimetabolite

Clinical Trials (5)

NCT05040464Phase 3Recruiting

Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled Trial

Started Aug 2021
NCT03930264Phase 1Completed

Bioequivalence of Azathioprine Suspension 10 mg/mL (Jayempi) Versus Azathioprine Tablet 50mg (Imurek®)

Started Apr 2019
30 enrolled
Therapeutic Equivalency
NCT02579733Phase 4Terminated

Azathioprine Based on Endoscopy After Clinical Remission in Moderate to Severe Ulcerative Colitis

Started Feb 2016
16 enrolled
Ulcerative Colitis
NCT01817972Phase 3Unknown

Cimzia Versus Cimzia Plus Azathioprine in the Treatment of Active Crohn's Disease

Started Mar 2013
65 enrolled
Crohn's Disease
NCT00608894Phase 2Terminated

LCP-Tacro vs. Azathioprine for the Treatment of Autoimmune Hepatitis

Started Dec 2007
13 enrolled
Autoimmune Hepatitis