NDAORALTABLET1 Generic Approved
Approved
Jun 1995
Lifecycle
LOE Approaching
Competitive Pressure
45/100
Clinical Trials
20
Data completeness
4/8 — Partial
Drug data last refreshed Yesterday
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
IMITREX (sumatriptan) is an oral small-molecule serotonin 1B receptor agonist approved in 1995 for acute treatment of migraine, cluster headache, and post-traumatic headache. It works by constricting blood vessels and reducing substances in the body that cause headache, pain, sensitivity to light and sound, nausea, vomiting, and other symptoms of migraine.
$0.232MPart D
LOE ApproachingDeclining
As a legacy product approaching loss of exclusivity with modest Medicare spending, the brand team is likely consolidating and shifting focus to retention and generic channel management.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
A STUDY TO EVALUATE THE EFFECT OF PF-06651600 ON PHARMACOKINETICS OF SINGLE DOSE SUMATRIPTAN IN HEALTHY PARTICIPANTS.
Started Jun 2020
10 enrolled
Healthy Volunteers
Sofusa System With Sumatriptan (KC5010) Phase 1 Dose Escalation Safety and PK Study (KCC-SMT-002)
Started Jan 2018
19 enrolled
Migraine Disorders
A Study of Lasmiditan When Given With Sumatriptan in Healthy Participants
Started Oct 2017
40 enrolled
Healthy
Low-Dose Naltrexone and Acetaminophen Combination and Sumatriptan in the Acute Treatment of Migraine With Nausea
Started Jun 2017
36 enrolled
Migraine With and Without Aura
Effect of Single Oral Doses of Lasmiditan When Coadministered With Single Oral Doses of Sumatriptan in Healthy Participants
Started Mar 2017
42 enrolled
Migraine
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.