ANDAINTRAVENOUSINJECTABLE
Approved
Feb 2002
Lifecycle
Post-LOE
Competitive Pressure
30/100
Data completeness
2/8 — Basic
IFOSFAMIDE/MESNA KIT (ifosfamide; mesna) by Teva is p450 isoenzymes to exert its cytotoxic activity. First approved in 2002.
Drug data last refreshed 22h ago
Mechanism of Action
P450 isoenzymes to exert its cytotoxic activity. Activation occurs by hydroxylation at the ring carbon atom forming the unstable intermediate 4‑hydroxyifosfamide and its ring-opened aldo tautomer, which decomposes to yield the cytotoxic and urotoxic compound acrolein and an alkylating…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Company
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.