IC-GREEN
LOE Approachingindocyanine green
NDAINJECTIONINJECTABLEPriority Review
Approved
Feb 1959
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
12
Data completeness
2/8 — Basic
Priority Review
Drug data last refreshed 4d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
IC-GREEN (Indocyanine Green) is a fluorescent dye injectable used for real-time surgical visualization and lymph node mapping across oncology and general surgery. It enables surgeons to identify sentinel lymph nodes, preserve critical structures (recurrent laryngeal nerve, parathyroid glands), and assess tissue perfusion intraoperatively. The dye fluoresces in the near-infrared spectrum when excited by specialized imaging systems, providing critical anatomical guidance during complex procedures.
LOE Approaching
As LOE approaches, the brand team is likely in maintenance mode with reduced headcount; career opportunities focus on maximizing remaining exclusivity and transitioning to post-LOE defense strategies.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (12)
The Value of Indocyanine Green-guided Near-infrared Fluorescence Technology in Tracing Sentinel Lymph Nodes During Esophagectomy
Started Jan 2026
144 enrolled
Esophageal CancerSentinel Lymph NodeLymphadenectomy+1 more
Real-Time Diagnosis of Life-Threatening Necrotizing Soft Tissue Infections (NSTI) Using Indocyanine Green (ICG) Kinetic Modeling
Started Sep 2025
420 enrolled
Necrotizing Fascitis
Indocyanine Green Fluoroscopy and SPY Angiography for the Assessment of Lymphatic Structure in Breast Cancer Patients at Risk for Breast Cancer-Related Lymphedema
Started Aug 2025
Use Of Indocyanine Green In Pancreas Surgery
Started May 2024
55 enrolled
Pancreatic Carcinoma
Does Fluorescence With or Without Indocyanine Green Improve Parathyroid Identification and Preservation
Started Apr 2024
417 enrolled
Parathyroid DysfunctionAdenoma
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.