HYPAQUE
LOE ApproachingNDAINJECTIONINJECTABLEPriority Review
Approved
Aug 1969
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
Priority Review
HYPAQUE by GE HealthCare is clinical pharmacology retrograde introduction of hypaque-cysto solution provides radiopacity of the contents of the urinary bladder. First approved in 1969.
Drug data last refreshed 3h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
HYPAQUE is a water-soluble contrast medium containing diatrizoate meglumine, administered by retrograde injection into the urinary bladder for radiographic visualization. It provides radiopacity of bladder contents and lower urinary tract structures during cystography and voiding cystourethrography to detect vesicoureteric reflux and urinary tract abnormalities. The drug works by providing radiopaque contrast that remains localized in the urinary tract with minimal systemic absorption.
LOE Approaching
This legacy diagnostic agent approaching loss of exclusivity faces moderate competitive pressure (30%), suggesting a contracting portfolio position with reduced team expansion opportunities.
Mechanism of Action
CLINICAL PHARMACOLOGY Retrograde introduction of HYPAQUE-CYSTO solution provides radiopacity of the contents of the urinary bladder. When used during micturation as a function test, it also opacifies the bladder neck and lower urinary tract. Continuous fluoroscopic and monitoring of urinary bladder…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.