HISTAMINE PHOSPHATE
LOE ApproachingNDAINJECTIONINJECTABLE
Approved
Apr 1939
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
HISTAMINE PHOSPHATE by Eli Lilly and Company is clinical pharmacology histamine acts as a potent vasodilator when released from mast cells during an allergic reaction. First approved in 1939.
Drug data last refreshed 8h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Histamine phosphate is an injectable small molecule used as a diagnostic agent in allergy testing to provoke immediate skin reactions in sensitized patients. It acts as a potent vasodilator by mimicking the histamine release from mast cells during allergic responses. The drug helps clinicians identify allergen sensitivities through controlled puncture testing with observable wheal and erythema formation.
LOE Approaching
Limited current hiring: this legacy diagnostic product shows minimal commercial activity with 0 linked jobs, indicating a small, mature team focused on maintenance rather than expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY Histamine acts as a potent vasodilator when released from mast cells during an allergic reaction. It is largely responsible for the immediate skin test reaction of a sensitive patient when challenged with an offending allergen. The effect of added Glycerin (50% v/v) to 1 mg/mL…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on histamine phosphate offers limited career growth due to minimal hiring (0 linked jobs) and an approaching loss of exclusivity. Positions are concentrated in specialized diagnostic medical affairs, quality operations, and regulatory maintenance roles rather than high-visibility commercial or R&D tracks.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.