HISTAMINE PHOSPHATE
LOE ApproachingNDAINJECTIONINJECTABLE
Approved
Apr 1939
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
HISTAMINE PHOSPHATE by Eli Lilly and Company is clinical pharmacology histamine acts as a potent vasodilator when released from mast cells during an allergic reaction. First approved in 1939.
Drug data last refreshed 2d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Histamine Phosphate is an injectable small-molecule diagnostic agent that acts as a potent vasodilator to induce immediate skin reactions in allergy testing. It is used to assess patient sensitivity to allergens by triggering wheals and erythema at the injection site. The drug has been approved since 1939 and remains a reference standard in allergic testing protocols.
LOE Approaching
Product is in late-stage lifecycle with minimal commercial growth trajectory and small team focus likely on maintenance rather than expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY Histamine acts as a potent vasodilator when released from mast cells during an allergic reaction. It is largely responsible for the immediate skin test reaction of a sensitive patient when challenged with an offending allergen. The effect of added Glycerin (50% v/v) to 1 mg/mL…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Histamine Phosphate offers limited career growth opportunity given zero linked job openings and LOE-approaching lifecycle status. Roles available are primarily defensive—focused on maintaining regulatory compliance, ensuring supply chain continuity, and managing a stable but non-expanding diagnostic franchise.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.