NDAINJECTIONINJECTABLE
Approved
Dec 1964
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Data completeness
3/8 — Basic
HEXADROL (dexamethasone sodium phosphate) by Aspen Surgical is clinical pharmacology naturally occurring glucocorticoids, (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. First approved in 1964.
Drug data last refreshed 20h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
HEXADROL (dexamethasone sodium phosphate) is a potent synthetic glucocorticoid administered by injection for systemic anti-inflammatory and immunomodulatory effects. It treats diverse conditions including ataxia telangiectasia, peripheral arterial disease, atopic keratoconjunctivitis, and perioperative inflammation by blocking inflammatory cytokine production and modifying immune responses. Unlike natural glucocorticoids, dexamethasone lacks significant sodium-retaining properties, making it suitable for prolonged anti-inflammatory therapy.
LOE Approaching
As loss of exclusivity approaches, the HEXADROL brand team likely faces portfolio consolidation pressure and may shift focus toward lifecycle management and cost optimization rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY Naturally occurring glucocorticoids, (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs, including dexamethasone, are primarily used for their potent…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (2)
Intra-Erythrocyte Dexamethasone Sodium Phosphate in Ataxia Telangiectasia Patients
Started Mar 2017
176 enrolled
Nervous System DiseaseGenetic Syndrome
Intra-Erythrocyte Dexamethasone Sodium Phosphate in Ataxia Teleangiectasia Patients
Started Feb 2011
22 enrolled
Nervous System DisorderGenetic Syndrome
Career Relevance
Worked on HEXADROL at Aspen Surgical? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.