HEPZATO

Growth

melphalan hydrochloride injection, powder, lyophilized, for solution

NDAINTRA-ARTERIALPOWDER
Approved
Aug 2023
Lifecycle
Growth
Competitive Pressure
0/100
Clinical Trials
1

Mechanism of Action

type. As a result, its cytotoxicity appears to be related to the extent of its interstrand cross-linking with DNA, probably by binding at the N7 position of guanine. It is active against both resting and rapidly dividing tumor cells.

Clinical Trials (1)

NCT07281924Phase 1/2Recruiting

Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis

Started Mar 2026
15 enrolled
Metastatic MelanomaLiver Metastases

Loss of Exclusivity

LOE Date
Sep 17, 2034
104 months away
Patent Expiry
Sep 17, 2034
Exclusivity Expiry
Aug 14, 2030

Patent Records (5)

Patent #ExpiryTypeUse Code
10098997
Nov 7, 2032
Product
10369264
Nov 7, 2032
Product
10569004
Nov 7, 2032
U-3683
11241522
Nov 7, 2032
Product
11633528
Nov 7, 2032
U-3675