HEPARIN SODIUM 10,000 UNITS IN SODIUM CHLORIDE 0.45%

LOE Approaching

heparin sodium

NDAINJECTIONINJECTABLE
Approved
Jan 1984
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
3

Mechanism of Action

protein, antithrombin III, to induce a conformational change, which markedly enhances the serine protease activity of Antithrombin II, thereby inhibiting the activated coagulation factors involved in the closing sequence, particularly Xa and IIa. Small amounts of heparin inhibit Factor Xa, and…

Clinical Trials (3)

NCT03113084Phase 1Suspended

Study With Heparin Sodium in Subcutaneous Administration

Started Aug 2022
NCT03125187Phase 1Suspended

Study With Heparin Sodium in Intravenous Administration

Started Feb 2021
NCT02181985Phase 3Completed

Full Dose Tenecteplase (TNK-tPA) Together With Heparin Sodium, Full Dose Tenecteplase With Enoxaparin, Half Dose Tenecteplase Together With Abciximab and Heparin Sodium in Patients With Acute Myocardial Infarction (AMI)

Started May 2000
5,989 enrolled
Myocardial Infarction