NDAORALTABLET
Approved
Mar 2025
Lifecycle
Growth
Competitive Pressure
30/100
Clinical Trials
14
Data completeness
4/8 — Partial
HEMICLOR (chlorthalidone) by R-Pharm US is long-acting oral diuretic with antihypertensive activity. First approved in 2025.
Drug data last refreshed 5h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
HEMICLOR (chlorthalidone) is a long-acting oral thiazide-like diuretic approved in March 2025 for hypertension management. It works by inhibiting sodium and chloride reabsorption in the ascending limb of Henle's loop, leading to increased sodium and water excretion that reduces blood volume and cardiac output. The drug's antihypertensive effect stems from sustained diuresis and electrolyte depletion.
Growth
Recently approved product in growth phase signals strong market expansion opportunity with expanding commercial team investment from R-Pharm US.
Mechanism of Action
long-acting oral diuretic with antihypertensive activity. Chlorthalidone produces diuresis with increased excretion of sodium and chloride. The site of action appears to be the cortical diluting segment of the ascending limb of Henle's loop of the nephron. The diuretic effects of chlorthalidone…
Pharmacologic Class:
Thiazide-like Diuretic
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (14)
Efficacy and Safety of Candesartan Associated With Chlorthalidone Versus Losartan Associated With Hydrochlorothiazide (Hyzaar®) in Essential Hypertension Control
Started Nov 2016
0Essential Arterial Hypertension
Efficacy and Safety of Candesartan Associated With Chlorthalidone in Essential Arterial Hypertension Control
Started Nov 2016
0Essential Arterial Hypertension
S-amlodipine+Chlorthalidone vs S-amlodipine+Telmisartan in Hypertension
Started Dec 2015
170 enrolled
Essential Hypertension
A Study to Evaluate the Effectiveness and Safety of a Fixed Dose Combination of Azilsartan Medoxomil and Chlorthalidone in Patients With High Blood Pressure Who do Not Achieve Target Blood Pressure Following Treatment With Azilsartan Medoxomil Alone
Started Oct 2011
507 enrolled
Essential Hypertension
Study to Evaluate the Efficacy and Safety of the Combination of Valturna and Amlodipine or Valturna and Chlorthalidone Versus Valturna Alone in Patients With Stage 2 Hypertension and Diabetes
Started May 2011
975 enrolled
HypertensionStage 2 HypertensionDiabetes
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.