HALCION

LOE Approaching

triazolam

NDAORALTABLETPriority Review
Approved
Nov 1982
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
3

Mechanism of Action

benzodiazepine. Triazolam exerts its effect for the short-term treatment of insomnia through binding to the benzodiazepine site of the gamma-aminobutyric acid-A (GABA A ) receptors in the brain and enhances GABA-mediated synaptic inhibition.

Pharmacologic Class:

Benzodiazepine

Clinical Trials (3)

NCT01888497Phase 3Completed

Next-Day Residual Effects of Gabapentin, Diphenhydramine and Triazolam on Simulated Driving Performance in Normal Volunteers

Started Jul 2013
59 enrolled
Healthy
NCT01421043Phase 1Completed

A Study to Determine Whether an Oral Drops Formulation of Triazolam is Bioequivalent to a Tablet Formulation in Healthy Subjects

Started Sep 2011
34 enrolled
Healthy
NCT01017926Phase 1Withdrawn

Triazolam Trial In Healthy Subjects To Compare Bioavailability Between Formulations Of Triazolam To Determine Their Bioequivalence In Terms Of Rate And Magnitude Of Absorption

Started Aug 2010
0
Healthy Volunteers