NDAVAGINALCREAM
Approved
Nov 1998
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
8
Data completeness
3/8 — Basic
GYNE-LOTRIMIN 3 (clotrimazole) by Bayer is clinical pharmacology clotrimazole is a broad-spectrum antifungal agent that is used for the treatment of dermal infections caused by various species of pathogenic dermatophytes, yeasts, and malassezia furfur . First approved in 1998.
Drug data last refreshed 5h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
GYNE-LOTRIMIN 3 is a broad-spectrum antifungal cream containing clotrimazole, indicated for vaginal yeast infections caused by Candida species and other fungal pathogens. The drug works by disrupting fungal cell membranes, causing leakage of intracellular components and inhibiting both dividing and growing organisms. Clotrimazole exhibits both fungistatic and fungicidal activity with minimal systemic absorption when applied topically or vaginally.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30), signaling transition from growth-stage team to legacy/maintenance operations.
Mechanism of Action
CLINICAL PHARMACOLOGY Clotrimazole is a broad-spectrum antifungal agent that is used for the treatment of dermal infections caused by various species of pathogenic dermatophytes, yeasts, and Malassezia furfur . The primary action of clotrimzole is against dividing and growing organisms. In vitro ,…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.