NDAORALTABLET
Approved
Jan 2015
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
1
Data completeness
7/8 — Comprehensive
GLYXAMBI (empagliflozin and linagliptin) by Boehringer Ingelheim is dipeptidyl peptidase 4 inhibitors [moa]. Approved for dipeptidyl peptidase 4 inhibitor [epc]. First approved in 2015.
Drug data last refreshed 18h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
GLYXAMBI is a fixed-dose combination oral tablet containing empagliflozin (SGLT2 inhibitor) and linagliptin (DPP-4 inhibitor) approved in 2015 for type 2 diabetes management. It works by dual mechanism: blocking renal glucose reabsorption and inhibiting incretin degradation to improve glycemic control. The combination targets patients requiring dual antidiabetic therapy with complementary mechanisms of action.
$137MPart D
Peak11.1 years to LOEProduct is at peak commercial maturity with 11+ years of patent protection remaining; brand teams are focused on market maintenance and margin optimization rather than growth expansion.
Mechanism of Action
Dipeptidyl Peptidase 4 Inhibitors
Pharmacologic Class:
Dipeptidyl Peptidase 4 Inhibitor
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Safety and Efficacy of the Combination of Empagliflozin and Linagliptin Compared to Linagliptin Alone Over 24 Weeks in Patients With Type 2 Diabetes
Started Feb 2013
607 enrolled
Diabetes Mellitus, Type 2
Why This Matters for Your Career
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.