GLUCAGEN by Novo Nordisk is clinical pharmacology glucagon increases blood glucose concentration and is used in the treatment of severe hypoglycemia. First approved in 1998.
Drug data last refreshed 2h ago · AI intelligence enriched 1w ago
GLUCAGEN (glucagon) is a parenteral emergency treatment for severe hypoglycemia that works by stimulating hepatic glycogenolysis to rapidly raise blood glucose. Administered via intramuscular, subcutaneous, or intravenous injection, it achieves peak glucose levels (~136–138 mg/dL) within 13–30 minutes. The drug has been the standard-of-care emergency hypoglycemia reversal agent for decades.
Product is approaching loss of exclusivity with modest Part D spending ($5M), signaling contraction of commercial opportunity and likely smaller brand team headcount.
CLINICAL PHARMACOLOGY Glucagon increases blood glucose concentration and is used in the treatment of severe hypoglycemia. Glucagon acts only on liver glycogen, converting it to glucose. Glucagon administered through a parenteral route relaxes smooth muscle of the stomach, duodenum, small bowel, and…
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Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
A Trial to Investigate the Safety and the Pharmacokinetic, Pharmacodynamic Characteristics of Two BioChaperone® Glucagon Formulations Compared to Marketed GlucaGen® in Subjects With T1DM
Pharmacokinetics (PK) and Pharmacodynamics (PD) of Mayne Glucagon for Injection Compared With Glucagen® (Novo Nordisk) in Healthy Volunteers
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Upgrade to Pro — $25/moGLUCAGEN offers stable, mission-critical commercial roles in a mature, high-stakes emergency medicine market, but limited growth trajectory due to LOE proximity and modest spending. Roles on this product emphasize customer relationship management, formulary access, and market defense rather than growth and innovation.