GLOPERBA
Peakcolchicine
NDAORALSOLUTION
Approved
Jan 2019
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
14
Mechanism of Action
Colchicine's effectiveness as a prophylactic treatment for gout has been postulated to be due to its ability to block neutrophil mediated inflammatory responses induced by monosodium urate crystals in synovial fluid. Colchicine disrupts the polymerization of β-tubulin into microtubules, thereby…
Pharmacologic Class:
Alkaloid
Indications (2)
Clinical Trials (5)
A Study to Evaluate Efficacy and Safety of Anakinra in Chinese Patients With Colchicine-resistent FMF
Started Sep 2025
3 enrolled
Familial Mediterranean Fever (FMF )
MACT (Mono Antiplatelet and Colchicine Therapy) Prospective Multicenter Study
Started Aug 2024
490 enrolled
Acute Coronary Syndrome
CorONa Virus edoxabaN ColchicinE (CONVINCE) COVID-19
Started Jan 2021
60 enrolled
SARS-CoV InfectionCOVID-19
Colchicine Prevents Myocardial Injury After Non-Cardiac Surgery Pilot Study
Started Sep 2020
0Myocardial InfarctionMyocardial InjuryMajor Adverse Cardiac Events+1 more
Anti-inflammatory Effects of Colchicine in PCI
Started May 2013
280 enrolled
Coronary Artery Disease
Loss of Exclusivity
LOE Date
Dec 20, 2037
143 months away
Patent Expiry
Dec 20, 2037