NDAORALCAPSULE
Approved
Aug 1976
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
17
Mechanism of Action
Alkylating Activity
Pharmacologic Class:
Alkylating Drug
Clinical Trials (5)
A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence
Started May 2024
90 enrolled
Glioblastoma
Phase II Trial of Romiplostim for Thrombocytopenia Induced by Lomustine at First Progression of MGMT Promoter-meth Glioblastoma
Started Sep 2022
0First Progression of MGMT Promoter-methylated Glioblastoma
Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First Progression
Started Jun 2022
0Glioblastoma
A Study to Evaluate Safety and Efficacy of L19TNF Plus Lomustine in Patients With Glioblastoma at First Progression
Started Feb 2021
142 enrolled
Glioblastoma
Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas
Started Feb 2015
266 enrolled
Glioblastoma