NDAORAL, RECTALSOLUTION
Approved
Jan 1958
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
GASTROGRAFIN (diatrizoate meglumine and diatrizoate sodium) by Bracco is clinical pharmacology the most important characteristic of contrast media is the iodine content. First approved in 1958.
Drug data last refreshed 4h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
GASTROGRAFIN is an oral and rectal contrast medium containing diatrizoate meglumine and diatrizoate sodium, used for radiographic visualization of the gastrointestinal tract. The iodine content provides radiodensity for contrast imaging, while the high osmolarity produces a mild laxative effect to enhance bowel visualization. It is indicated for diagnostic imaging of the esophagus, stomach, small intestine, and colon.
LOE Approaching
As a mature legacy diagnostic contrast product approaching loss of exclusivity, the brand team is likely small and focused on maintaining market presence rather than expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY The most important characteristic of contrast media is the iodine content. The relatively high atomic weight of iodine contributes sufficient radiodensity for radiographic contrast with surrounding tissues. Diagnostic enteral radiopaque agents have few known pharmacological…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.