GALZIN
LOE Approachingzinc acetate
NDAORALCAPSULE
Approved
Jan 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
GALZIN (zinc acetate) is clinical pharmacology introduction wilson's disease (hepatolenticular degeneration) is an autosomal recessive metabolic defect in hepatic excretion of copper in the bile, resulting in accumulation of excess copper in the liver, and subsequently in other organs, including the brain, kidneys, eyes, bone, and muscles. First approved in 1997.
Drug data last refreshed 18h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
GALZIN (zinc acetate) is an oral small-molecule agent for Wilson's disease, a rare autosomal recessive copper metabolism disorder. It works by inducing metallothionein production in enterocytes, which binds dietary and endogenously secreted copper in the intestine, preventing systemic absorption and promoting fecal excretion. The drug is indicated for both initial detoxification and long-term maintenance therapy in symptomatic Wilson's disease patients.
LOE Approaching
With LOE approaching and minimal current job openings, the GALZIN brand team is likely optimizing maintenance operations rather than expanding headcount.
Mechanism of Action
CLINICAL PHARMACOLOGY Introduction Wilson's disease (hepatolenticular degeneration) is an autosomal recessive metabolic defect in hepatic excretion of copper in the bile, resulting in accumulation of excess copper in the liver, and subsequently in other organs, including the brain, kidneys, eyes,…
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
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