GABITRIL

LOE Approaching

tiagabine hydrochloride

NDAORALTABLET
Approved
Sep 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
5

Mechanism of Action

Mechanism of Action The precise mechanism by which tiagabine exerts its antiseizure effect is unknown, although it is believed to be related to its ability, documented in in vitro experiments, to enhance the activity of gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter in the…

Clinical Trials (5)

NCT00214994Phase 3Completed

Study to Evaluate the Safety and Efficacy of GABITRIL Treatment in Adults With Generalized Anxiety Disorder.

Started Jan 2005
Anxiety Disorders
NCT00236015Phase 3Completed

A 10-Week Efficacy and Safety Study of Gabitril in the Treatment of Adults With Generalized Anxiety Disorder

Started Nov 2004
880 enrolled
Anxiety Disorder
NCT00236054Phase 3Completed

A 10-Week Efficacy and Safety Study for of Gabitril in the Treatment of Adults With Generalized Anxiety Disorder

Started Oct 2004
440 enrolled
Generalized Anxiety Disorder
NCT00236067Phase 3Completed

A 10-Week Study for Efficacy and Safety Study of Gabitril in the Treatment of Adults With Generalized Anxiety Disorder

Started Oct 2004
440 enrolled
Generalized Anxiety Disorder
NCT00233675Phase 3Completed

Evaluate the Safety of GABITRIL in Adults With Generalized Anxiety Disorder

Started Aug 2003
General Anxiety Disorder